منابع مشابه
Effect of different synthetic matrix metalloproteinase inhibitors on composite-dentin microtensile bond strength durability
Background and Aims: Despite patient’s demand increased for tooth color restorations, the stable bond between dentin and composite is a challenge in dentistry. Dentin protease activation is responsible for dentin-resin bond failure. The aim of this study was to determine the best pretreatment agent to inhibit matrix metalloproteinase and increase resin-dentin bond durability. Materials and Met...
متن کاملRecent Advancement of MMP Inhibitors
Volume 4 • Issue 2 • 1000e112 Adv Tech Biol Med ISSN: 2379-1764 ATBM, an open access journal Matrix metalloproteinase (MMPs) are a family of zinc dependent endopeptidases that play a significant role in cancer as well as in numerous other diseases [1]. It degrades the extracellular matrix (ECM) components and controlled remodeling of ECM is essential for invasion, metastasis and growth of vario...
متن کاملRole of matrix metalloproteinases (MMPs) and MMP inhibitors on intracranial aneurysms: a review article
Cerebrovascular disease is one of the leading causes of death in the world, and about one-fourth of cerebrovascular deaths are due to ruptured cerebral aneurysms (CA). Hence it is important to find a way to reduce aneurysm formation and its subsequent morbidity and mortality. Proteolytic activity capable of lysing gelatin has been shown to be increased in aneurysm tissue and expressio...
متن کاملDentin sialophosphoprotein is processed by MMP-2 and MMP-20 in vitro and in vivo.
Dentin sialophosphoprotein (DSPP) is a major secretory product of odontoblasts and is critical for proper tooth dentin formation. During dentinogenesis, DSPP is proteolytically cleaved into smaller subunits. These cleavages are proposed activation steps, and failure to make these cleavages is a potential cause of developmental tooth defects. We tested the hypothesis that dentin-resident matrix ...
متن کاملMorphological effects of MMPs inhibitors on the dentin bonding.
Matrix metalloproteinases (MMPs) have been studied extensively, and MMP inhibitors have been used as dental pretreatment agents prior to dentin bonding because they reduce collagen fiber degradation and improve bonding strength. However, morphologic characteristics of the collagen network after etching and of the post-adhesive dentin hybrid layers (DHL) after MMP inhibitors pretreatment have no...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Dental Research
سال: 2014
ISSN: 0022-0345,1544-0591
DOI: 10.1177/0022034514538046